In order to achieve rapid heating and cooling of microfluidic polymerase chain reaction（PCR）

a temperature control system is designed based on thermoelectric cooler（TEC）.Through thermal analysis on microfluidic PCR chip of temperature controlling object

parameters of TEC are determined

as well as the relationship between the cooling efficiency and heat radiation performance are studied.On this basis

a fin-type heat pipe high performance heat radiator is designed

its mechanism of heat transfer

the heat transfer routes

and thermal resistance are analyzed

finite element model（FEM） is set up

and experimental test on heat pipe heat radiator is carried out.The experimental results indicate that the average heating and cooling rate of temperature control system can achieve 7.48 ℃/s

and lay a good foundation for quickly and accurately heating and cooling temperature control of microfluidic PCR system.