Design of a microsystem based on color recognition for diagnosis and treatment of intestinal tract bleeding

YAN Xue-ping1; LIU Hong-ying1; PI Xi-tian1; WANG Gang1; ZHU Lan1; ZHENG Xiao-lin1

doi:10.13873/j.1000-97872011.11.016

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Design of a microsystem based on color recognition for diagnosis and treatment of intestinal tract bleeding

更新时间：2025-09-11

- Design of a microsystem based on color recognition for diagnosis and treatment of intestinal tract bleeding
- Vol. 30, Issue 11, Pages: 92-95(2011)
- 作者机构：
  
  1. 重庆大学生物工程学院生物流变科学与技术教育部重点实验室
  2. 重庆大学新型微纳器件与系统技术国防重点学科实验室
- 作者简介：
- 基金信息：
- DOI：10.13873/j.1000-97872011.11.016
  CLC： R318.6
- Published：2011
- 稿件说明：
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[1]燕雪萍,刘洪英,皮喜田,王刚,朱兰,郑小林.基于颜色识别的肠道出血诊疗微系统设计[J].传感器与微系统,2011,30(11):92-95.

YAN Xue-ping1, LIU Hong-ying1, PI Xi-tian1, et al. Design of a microsystem based on color recognition for diagnosis and treatment of intestinal tract bleeding[J]. 2011, 30(11): 92-95.
[1]燕雪萍,刘洪英,皮喜田,王刚,朱兰,郑小林.基于颜色识别的肠道出血诊疗微系统设计[J].传感器与微系统,2011,30(11):92-95. DOI： 10.13873/j.1000-97872011.11.016.

YAN Xue-ping1, LIU Hong-ying1, PI Xi-tian1, et al. Design of a microsystem based on color recognition for diagnosis and treatment of intestinal tract bleeding[J]. 2011, 30(11): 92-95. DOI： 10.13873/j.1000-97872011.11.016.

摘要

提出了一种可自动识别肠道出血区域并具有药物释放功能的微系统方案

设计了基于颜色传感器的出血检测模块和可用于粘附肠道血液的特殊吸附性薄片。引入HSL（色相Hue、饱和度Saturation、亮度Light）颜色空间法

根据出血与非出血区域色相H值的差异来实现肠道出血的智能识别

针对微量出血和较大量出血2种情况提出了不同的识别算法。实验结果表明:根据色相H值的变化可将血红蛋白浓度C>2.375 g/L的人体血液样本与无血红蛋白的模拟肠液明显区分开。当满足设定的出血阈值条件时

智能胶囊可成功触发药物释放

整个系统结构设计简单、可靠。

Abstract

A microsystem that could automatically identify the intestinal tract bleeding region and delivery drugs is proposed here.In the system

the bleeding detection module is designed based on the color sensor

and a film with special absorbability is utilized for the blood to adhere to.HSL（Hue

Saturation

Light）color space method is adopted

two different recognition algorithms with respect to slight and comparatively massive hemorrhage are proposed.Test results demonstrate that this system could distinguish the blood samples from the simulative intestinal fluid（SIF）without hemoglobin（Hb）

according to change of H value

when the concentration of Hb in blood samples is above 2.375g/L.Additionally

this system with simplicity and reliability could successfully trigger the drug release when the values of hue satisfy the established threshold.

关键词

Keywords

references

An intelligent electronic capsule system for automated detection of gastrointestinal bleeding [J]. Hong-ying LIU1,Gang WANG1,Kang WEI1,Xi-tian PI1,2,Lan ZHU1,Xiao-lin ZHENG1,2,Zhi-yu WEN2 (1Key Laboratory of Biorheological Science and Technology of Ministry of Education,College of Bioengineering,Chongqing University,Chongqing 400030,China) (2Key Laboratories for National Defense Science and Technology of Innovative Micro-Nano Devices and System Technology,Chongqing University,Chongqing 400030,China). Journal of Zhejiang University-Science B（Biomedicine & Biotechnology） . 2010(12)

阴离子交换树脂固相萃取分离全血中血红蛋白的研究 [J]. 陈旭伟,仲崇慧,王建华. 分析科学学报 . 2009(03)

新型颜色传感器TCS230应用于CRRT机漏血检测的可行性研究 [J]. 潘海鸿,陈琳,段素强,梁成业,杨微. 中国医学物理学杂志 . 2008(05)

How much helpful is the capsule endoscopy for the diagnosis of small bowel lesions? [J]. Osman Ersoy,Bulent Sivri,Serap Arslan,Figen Batman,Yusuf Bayraktar. World Journal of Gastroenterology . 2006(24)

A novel micro-fabricated thruster for drug release in remote controlled capsule [J] . Xitian Pi,Yulin Lin,Kang Wei,Hongying Liu,Gang Wang,Xiaolin Zheng,Zhiyu Wen,Deyu Li. Sensors & Actuators: A. Physical . 2010 (2)

Non-invasive method to detect and locate haemorrhagic focus of GI tract [J] . J. Shi,G. -Z. Yan,K. -D. Wang,Y. Fang. Journal of Medical Engineering & Technology . 2007 (2)

Ulcerative Jejunoileitis: A Complication of Celiac Sprue Simulating Crohn’s Disease Diagnosed with Capsule Endoscopy （PillCam） [J] . Charlene A. LePane,Jamie S. Barkin,Javier Parra,Todd Simon. Digestive Diseases and Sciences . 2007 (3)

Clinical impact of push enteroscopy in patients with gastrointestinal bleeding of unknown origin [J] . Alexis Bezet,Emmanuel Cuillerier,Bruno Landi,Philippe Marteau,Christophe Cellier. Clinical Gastroenterology and Hepatology . 2004 (10)

The clinical utility of technetium 99m-labeled bleeding scans in the evaluation of acute lower GI hemorrhage [J] . Gregory D Olds,Michael V Sivak,Richard C.K Wong. The American Journal of Gastroenterology . 2002 (9)

Value of angiography in diagnosis and therapy of acute upper gastrointestinal hemorrhage [J] . Digestive Diseases and Sciences . 1981 (7)

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