Theoretical study on temperature property of the SPR biosensor

YANG Jun1; TIAN Hao1; XIE Lin2; YANG Jing3; CAO Yi4

doi:10.13873/j.1000-97872011.10.032

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Theoretical study on temperature property of the SPR biosensor

更新时间：2025-09-11

- Theoretical study on temperature property of the SPR biosensor
- Vol. 30, Issue 10, Pages: 69-71+74(2011)
- 作者机构：
  
  1. 重庆大学生物工程学院
  2. 第三军医大学大坪医院野战外科研究所眼科
  3. 重庆通信学院军事信息工程系
  4. 重庆城市管理职业学院电子信息工程系
- 作者简介：
- 基金信息：
- DOI：10.13873/j.1000-97872011.10.032
  CLC： TP212.3
- Published：2011
- 稿件说明：
移动端阅览
[1]杨军,田浩,谢琳,杨静,曹毅.SPR生物传感器温度特性的理论研究[J].传感器与微系统,2011,30(10):69-71+74.

YANG Jun1, TIAN Hao1, XIE Lin2, et al. Theoretical study on temperature property of the SPR biosensor[J]. 2011, 30(10): 69-71+74.
[1]杨军,田浩,谢琳,杨静,曹毅.SPR生物传感器温度特性的理论研究[J].传感器与微系统,2011,30(10):69-71+74. DOI： 10.13873/j.1000-97872011.10.032.

YANG Jun1, TIAN Hao1, XIE Lin2, et al. Theoretical study on temperature property of the SPR biosensor[J]. 2011, 30(10): 69-71+74. DOI： 10.13873/j.1000-97872011.10.032.

摘要

表面等离子体共振（SPR）生物传感器在生物大分子检测时具有非常高的理论分析精度

但在实际应用过程中传感响应特性容易受到环境温度的影响。在小型化SPR传感器中由于缺乏温度控制模块

这种情况尤为明显。利用理论模型分析研究了环境温度变化对传感系统中光源、棱镜、金属薄膜和待测溶液等不同介质、光学检测器等的物理特性的影响以及由此引起的传感响应曲线的变化。研究结果表明:随着温度的增加

传感响应曲线中共振角度会相应减小。这一研究为小型化SPR生物传感器的研究开发提供了重要依据。

Abstract

Surface plasmon resonance（SPR） biosensor has very high theoretically analytical precision in the detection of biological macromolecules.However

in practical application

its responding characteristics are easily impacted by the environmental temperature.This case is more obvious in miniaturized device for temperature controlling module is not integrated in it.A theoretical mode is used to analyze the impact of the environmental temperature on the characteristics of the light source

prism

metal film

analyte solusion

and detector.The result shows that with the increase of temperature

resonance angle in the response curve will decrease accordingly.This study provides an important basis for the research and development of miniaturized SPR biosensor.

关键词

Keywords

references

便携式表面等离子体共振传感器温度特性 [J]. 林开群,鲁拥华,罗艳华,陈勇,郑荣升,谢志国,王沛,明海. 光子学报 . 2009(09)

温度对表面等离子体振荡传感器的作用 [J]. 吕晖,马晓红,赵华凤. 光电工程 . 2009(06)

基于反射光强度检测的棱镜SPR传感器 [J]. 曾捷,梁大开,杜艳,曾振武. 光电子.激光 . 2007(02)

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