Simulation of surface plasmon resonance sensor

XING Bing-bing1; GENG Zhao-xin1; WANG Ji-ye1; NIU Jin-zhen1; WANG Jing1

doi:10.13873/j.1000-97872010.07.021

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Simulation of surface plasmon resonance sensor

更新时间：2025-09-11

- Simulation of surface plasmon resonance sensor
- Vol. 29, Issue 7, Pages: 56-59(2010)
- 作者机构：
  
  1. 中央民族大学信息工程学院
  2. 北京大学微电子研究院微米/纳米加工技术国家重点实验室
- 作者简介：
- 基金信息：
- DOI：10.13873/j.1000-97872010.07.021
  CLC： TP212
- Published：2010
- 稿件说明：
移动端阅览
[1]邢冰冰,耿照新,王继业,钮金真,王静.表面等离子体共振传感器的仿真[J].传感器与微系统,2010,29(07):56-59.

XING Bing-bing1, GENG Zhao-xin1, WANG Ji-ye1, et al. Simulation of surface plasmon resonance sensor[J]. 2010, 29(7): 56-59.
[1]邢冰冰,耿照新,王继业,钮金真,王静.表面等离子体共振传感器的仿真[J].传感器与微系统,2010,29(07):56-59. DOI： 10.13873/j.1000-97872010.07.021.

XING Bing-bing1, GENG Zhao-xin1, WANG Ji-ye1, et al. Simulation of surface plasmon resonance sensor[J]. 2010, 29(7): 56-59. DOI： 10.13873/j.1000-97872010.07.021.

摘要

为了得到基于相位检测、角度检测和波长检测的表面等离子体共振（SPR）生物传感器的高检测精度

利用Matlab建立了Kretschmann模型SPR传感器的数值仿真软件。系统地进行了棱镜折射率、测试介质折射率、金膜的厚度等因素对3种不同检测方式的SPR曲线的影响。理论分析结果表明:角度调制时与介质折射率增加时

SPR角也相应增加

相位检测对传感层的折射率具有选择性。

Abstract

To realize high detection precision of surface plasmon resonance（ SPR） biosensor based on phase detection

angle detection and wavelength detection

numerical simulation software for SPR sensor with Kretschmann model was set up using Matlab. Effect of refractive index （ RI） of prism

RI of sample and the thickness of Au thin film on SPR curve of three different detecting method is described. Theoretical analysis results show that the SPR angle increase with the increase of RI of sample when the angle modulation. The phase detection has selectivity to the refractive index of the sensing layer.

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Keywords

references

Towards integrated and sensitive surface plasmon resonance biosensors: A review of recent progress [J] . X.D. Hoa,A.G. Kirk,M. Tabrizian. Biosensors and Bioelectronics . 2007 (2)

Recent advances in surface plasmon resonance based techniques for bioanalysis [J] . K. Scott Phillips,Quan Cheng. Analytical and Bioanalytical Chemistry . 2007 (5)

Present and future of surface plasmon resonance biosensors [J] . Analytical and Bioanalytical Chemistry . 2003 (3)

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