Optimized design about microchannel shape of sample injection on microchip electrophoresis

TIAN Li; LIU Xiao-wei; WANG Wei; HU Zi-jie

doi:10.13873/j.1000-97872008.10.012

Chinese

您当前的位置：

首页 >

文章列表页 >

Optimized design about microchannel shape of sample injection on microchip electrophoresis

更新时间：2025-09-11

- Optimized design about microchannel shape of sample injection on microchip electrophoresis
- Vol. 27, Issue 10, Pages: 82-85(2008)
- 作者机构：
  
  哈尔滨工业大学MEMS中心
- 作者简介：
- 基金信息：
- DOI：10.13873/j.1000-97872008.10.012
  CLC： TN492
- Published：2008
- 稿件说明：
移动端阅览
[1]田丽,刘晓为,王蔚,胡自洁.电泳微芯片进样口与微沟道形状的优化设计[J].传感器与微系统,2008,27(10):82-85.

TIAN Li, LIU Xiao-wei, WANG Wei, et al. Optimized design about microchannel shape of sample injection on microchip electrophoresis[J]. 2008, 27(10): 82-85.
[1]田丽,刘晓为,王蔚,胡自洁.电泳微芯片进样口与微沟道形状的优化设计[J].传感器与微系统,2008,27(10):82-85. DOI： 10.13873/j.1000-97872008.10.012.

TIAN Li, LIU Xiao-wei, WANG Wei, et al. Optimized design about microchannel shape of sample injection on microchip electrophoresis[J]. 2008, 27(10): 82-85. DOI： 10.13873/j.1000-97872008.10.012.

摘要

基于电渗流场的理论

建立电泳芯片的不同结构模型

以计算流体力学（CFD）方法来模拟不同设计参数和电压组合下的电泳微芯片微沟道中流体流动现象。最终优化基本型毛细管微沟道交叉口形状为矩形

微沟道宽度为20μm

进样与分离场强为200

50 V/cm。为在有限芯片面积下增加有效分离距离

设计螺旋形沟道电泳芯片模式。

Abstract

Based on the theory of electroosmosis flow

the different structure models of microchip electrophoresis are set up

and the fluid flow situation in the microchannel are simulated with the CFD software at the different design parameter and the voltage combination.The final simulation results indicate that the shape of sample injection on the microchip electrophoresis is the rectangle

the width of the microchannel is 20μm

the electric field strength of the sample injection and separation is between 200

50V/cm.Also a kind of spiral microchannel mode is optimized with the better separation efference in order to increase the efficiency separation distance on the limited microchip area.

关键词

Keywords

references

电泳芯片跑道效应CFD软件仿真与优化设计 [J]. 田丽,刘晓为,王蔚,胡自洁. 传感技术学报 . 2006(05)

毛细管电泳芯片分离DNA片段的实验研究 [J]. 田丽,陈伟平,刘晓为,王喜莲. 哈尔滨工业大学学报 . 2004(08)

毛细管电泳芯片微沟道内电场分布的数值计算 [J]. 范博源,闫卫平,马灵芝. 分析试验室 . 2003(04)

Views

109

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Design of dual-heating temperature and humidity sensors for building energy consumption

Related Author

ZOU Yongqi

LIU Qingquan

JIN Wei

LIU Hong

WANG Ke

PAN Xu

Related Institution

Collaborative Innovation Center of Atmospheric Environment and Equipment Technology,Nanjing University of Information Science and Technology

2.Jiangsu Key Laboratory of Meteorological Observation and Information Processing,Nanjing University of Information Science and Technology

3.School of Electronic Science and Engineering,Nanjing University of Information Science and Technology

⁰