Design of integrated capillary electrophoresis chip

LIU Xiaowei; TIAN Li; HUO Mingxue; WANG Mei  

doi:10.13873/j.1000-97872003.02.022

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Design of integrated capillary electrophoresis chip

更新时间：2025-09-11

- Design of integrated capillary electrophoresis chip
- Issue 2, Pages: 61-64(2003)
- 作者机构：
  
  1. 哈尔滨工业大学中心
  2. 哈尔滨工业大学中心,黑龙江,哈尔滨,150001
- 作者简介：
- 基金信息：
- DOI：10.13873/j.1000-97872003.02.022
  CLC： TN402
- Published：2003
- 稿件说明：
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[1]刘晓为,田丽,霍明学,王美.集成毛细管电泳芯片的设计[J].传感器技术,2003(02):61-64.

LIU Xiaowei, 　TIAN Li, 　HUO Mingxue, et al. Design of integrated capillary electrophoresis chip[J]. 2003, (2): 61-64.
[1]刘晓为,田丽,霍明学,王美.集成毛细管电泳芯片的设计[J].传感器技术,2003(02):61-64. DOI： 10.13873/j.1000-97872003.02.022.

LIU Xiaowei, 　TIAN Li, 　HUO Mingxue, et al. Design of integrated capillary electrophoresis chip[J]. 2003, (2): 61-64. DOI： 10.13873/j.1000-97872003.02.022.

摘要

利用ANSYS软件对集成毛细管电泳芯片微沟道内样品流动情况进行模拟

获得了不同进样模式下微沟道的结构与流体流速之间的关系

并以此为依据对芯片整体结构参数进行设计:毛细管沟道最终尺寸为宽度16μm

深度10μm

有效分离长度为3.5cm的圆角转弯形沟道

从而确定整个芯片设计。

Abstract

?The fluid distribution in the microchannel of ICEC （Integrated Capillary Electrophoresis Chip） was simulated using ANSYS software.The relations between the microchannel structure and flow velocity under different sample injection modes were obtained.Then the optimized channel structure was chosen by the width of 16?μm

the depth of the chip was determined 10?μm and the effective dividing length of 3.5?cm with round corner channel.The chip structure was designed.

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references

集成毛细管电泳芯片系统的制作、测试及应用 [J]. 金亚,罗国安,汤扬华,周兆英. 分析科学学报 . 2001(02)

集成毛细管电泳芯片研究进展 [J]. 金亚,罗国安,王如骥. 色谱 . 2000(04)

缩微芯片实验室 [J]. 王琪,方向东,王小宁,戚正武. 生命的化学 . 2000(02)

集成毛细管电泳芯片及其制作技术的进展 [J]. 吴友谊,吴明嘉. 分析测试技术与仪器 . 1999(03)

毛细管电泳导论[M]. 科学出版社 , 林炳承著, 1996

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