Finite element analysis on conductance properties of nanopore single molecule sensor

WU Gen-sheng; ZHANG Hong-wei; YU Bo; MA Dong-qin; SONG Fu-lei

doi:10.13873/j.1000-9787(2018)05-0019-04

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Finite element analysis on conductance properties of nanopore single molecule sensor

更新时间：2025-09-11

- Finite element analysis on conductance properties of nanopore single molecule sensor
- Issue 5, Pages: 19-22(2018)
- 作者机构：
  
  南京林业大学机械电子工程学院
- 作者简介：
- 基金信息：
- DOI：10.13873/j.1000-9787(2018)05-0019-04
  CLC： TP212
- Published：2018
- 稿件说明：
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WU Gen-sheng, ZHANG Hong-wei, YU Bo, et al. Finite element analysis on conductance properties of nanopore single molecule sensor[J]. 2018, (5): 19-22.
DOI：

WU Gen-sheng, ZHANG Hong-wei, YU Bo, et al. Finite element analysis on conductance properties of nanopore single molecule sensor[J]. 2018, (5): 19-22. DOI： 10.13873/j.1000-9787(2018)05-0019-04.

摘要

主要从纳米孔结构角度

考虑生物分子在纳米孔内的位阻效应影响。运用有限元模拟方法分别模拟了3类常见纳米孔的电导

并比较了3种不同纳米孔在检测纳米杆通过纳米孔时的相对堵塞电流值大小。研究了纳米杆上带有亚结构时

在3种纳米孔内的电流堵塞效应的差异。研究方法有助于进一步理解纳米孔结构对检测生物分子的影响。

Abstract

Mainly consider influence of steric effect of biomolecule inside the nanopore from the perspective of nanopore structure.Finite element simulation method is used to simulate conductance of three common types of nanopore.The relative blockade current value of three nanopores while the testing nanorod is passing through the nanpores are compared.In the meantime

the difference of current blockade effect of nanorod with substructure in three nanopores is also researched. This work is helpful to understand the influence of nanopore structure on detecting biomolecules.

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