Design and implementation of portable electrical stimulator for cell culturing

DENG Wei-li; CHU Wen-jun; HUANG Xin-jie

doi:10.13873/j.1000-9787(2017)05-0113-03

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Design and implementation of portable electrical stimulator for cell culturing

更新时间：2025-09-11

- Design and implementation of portable electrical stimulator for cell culturing
- Vol. 36, Issue 5, Pages: 113-115+119(2017)
- 作者机构：
  
  1. 西南交通大学材料科学与工程学院
  2. 西南交通大学机械工程学院
- 作者简介：
- 基金信息：
- DOI：10.13873/j.1000-9787(2017)05-0113-03
  CLC： TP368.12;R329.2
- Published：2017
- 稿件说明：
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[1]邓维礼,楮文俊,黄欣杰.用于细胞培养的便携式电刺激器设计与实现[J].传感器与微系统,2017,36(05):113-115+119.

DENG Wei-li, CHU Wen-jun, HUANG Xin-jie. Design and implementation of portable electrical stimulator for cell culturing[J]. 2017, 36(5): 113-115+119.
[1]邓维礼,楮文俊,黄欣杰.用于细胞培养的便携式电刺激器设计与实现[J].传感器与微系统,2017,36(05):113-115+119. DOI： 10.13873/j.1000-9787(2017)05-0113-03.

DENG Wei-li, CHU Wen-jun, HUANG Xin-jie. Design and implementation of portable electrical stimulator for cell culturing[J]. 2017, 36(5): 113-115+119. DOI： 10.13873/j.1000-9787(2017)05-0113-03.

摘要

设计了一种以STC89C51单片机为核心的数字化多功能电刺激器

可根据用户需要产生直流、方波、正弦波、三角波和锯齿波共5种类型的电刺激信号

同时可实现各个波形的幅值和频率可调

其幅值输出范围为0

频率范围为0

0 k Hz

实现相同温度、湿度及培养基环境条件下

细胞培养过程中的电信号刺激以及高通量筛选。

Abstract

A digital multifunction electrical stimulator based on MCU STC89C51 is designed

which can generate five different types of waves

direct current

sine wave

square wave

triangular wave and sawtooth wave

respectively. At the same time

the amplitude and frequency of each waveform can be adjusted according to the requirement of users. Its amplitude output range is 0

5 V

and the frequency range is 0

10 k Hz. It is able to use to electrical signal stimulation and high throughput screening in cell culturing

under the same temperature

humidity and medium environment conditions.

关键词

Keywords

references

细胞电刺激器的设计与实现 [J]. 何猛,邹远文,李晋川,黄学进,何刚. 实验科学与技术 . 2015(03)

基于单片机的低频信号发生器设计 [J]. 任小青,王晓娟,田芳. 现代电子技术 . 2014(16)

基于单片机的智能信号发生器设计与仿真 [J]. 董亚男,马俊,周泉,李金林. 电子测量技术 . 2014(01)

用于治疗功能性胃肠疾病的植入式电刺激器设计 [J]. 韩云端,姜萍萍,王永兵,颜国正. 传感器与微系统 . 2013(12)

基于DAC0832和AT89S52的信号发生器设计 [J]. 李庭贵. 电子科技 . 2012(06)

基于可调式稳压器LM317的直流稳压电源 [J]. 冯平,张治中. 电子测试 . 2009(05)

单片机的C语言应用程序设计[M]. 北京航空航天大学出版社 , 马忠梅等, 2007

DC Electric Fields Direct Breast Cancer Cell Migration, Induce EGFR Polarization, and Increase the Intracellular Level of Calcium Ions [J] . Dan Wu,Xiuli Ma,Francis Lin. Cell Biochemistry and Biophysics . 2013 (3)

Electrical stimulation of human embryonic stem cells: Cardiac differentiation and the generation of reactive oxygen species [J] . Elena Serena,Elisa Figallo,Nina Tandon,Christopher Cannizzaro,Sharon Gerecht,Nicola Elvassore,Gordana Vunjak-Novakovic. Experimental Cell Research . 2009 (20)

Electrostimulation induces cardiomyocyte predifferentiation of fibroblasts [J] . Jorge A. Genovese,Cristiano Spadaccio,Jason Langer,Jaclyn Habe,Johnna Jackson,Amit N. Patel. Biochemical and Biophysical Research Communications . 2008 (3)

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