Construction and application of fluorescence sensor based on silver nanoparticles and carbon quantum dots

LI Na; LI Meng; ZHANG He; MAO Yongqiang

doi:10.13873/J.1000-9787(2020)11-0004-03

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Construction and application of fluorescence sensor based on silver nanoparticles and carbon quantum dots

更新时间：2025-09-11

- Construction and application of fluorescence sensor based on silver nanoparticles and carbon quantum dots
- Issue 11, Pages: 4-6(2020)
- 作者机构：
  
  1. 辽宁工程技术大学化学与化工研究所
  2. 辽宁工程技术大学理学院
- 作者简介：
- 基金信息：
- DOI：10.13873/J.1000-9787(2020)11-0004-03
  CLC： TP212
- Published：2020
- 稿件说明：
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LI Na, LI Meng, ZHANG He, et al. Construction and application of fluorescence sensor based on silver nanoparticles and carbon quantum dots[J]. 2020, (11): 4-6.
DOI：

LI Na, LI Meng, ZHANG He, et al. Construction and application of fluorescence sensor based on silver nanoparticles and carbon quantum dots[J]. 2020, (11): 4-6. DOI： 10.13873/J.1000-9787(2020)11-0004-03.

摘要

基于荧光共振能量转移效应构建银纳米粒子(Ag NPs)/碳量子点(CQDs)荧光传感器

用于氨苄青霉素(AMP)的快速检测。实验结果表明:CQDs将能量转移给Ag NPs

导致CQDs荧光猝灭

而加入氨苄青霉素使CQDs荧光得到恢复。在优化实验条件下

体系荧光恢复值与氨苄青霉素浓度在4. 0～48. 0μg/m L范围内呈良好的线性关系

检出限为0. 1μg/m L。该荧光传感器用于氨苄西林胶囊中氨苄青霉素含量的测定

回收率为98. 0%～104. 5%

表明该荧光传感器可用于药物中氨苄青霉素含量的定量检测。

Abstract

A fluorescence sensor based on silver nanoparticles（ Ag NPs） and carbon quantum dots（ CQDs） for rapid determination of ampicillin（ AMP） is constructed by fluorescence resonance energy transfer effect. Experimental result shows that effective enery transfered from CQDs to Ag NPs

which results in fluorescence quenching of CQDs. Addiing ampicillin makes the fluorescence intensity of CQDs significantly recovered. Under optimum experimental conditions

the recovery value of fluorescence intensity with ampicillin concentration exhibits good linear relationship in range of 4. 0～ 48. 0 μg/m L

and the detection limit is 0. 1 μg/m L. The content of ampicillin in ampicillin capsules is determined by this fluorescence sensor with recoveries of 98. 0 %～ 104. 5 %

which indicats that the proposed fluorescence sensor can be used for practical detection of ampicillin in drugs.

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