Research progress of MOFs-based aptamer sensors in detection of tumor markers

QUE Longbin; Gu Xin; PAN Hongzhi

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Research progress of MOFs-based aptamer sensors in detection of tumor markers

Survey & Review | 更新时间：2026-03-01

- Research progress of MOFs-based aptamer sensors in detection of tumor markers
- Vol. 45, Issue 2, Pages: 1-5(2026)
- 作者机构：
  
  1. 上海理工大学健康科学与工程学院,上海,200093
  2. 上海健康医学院协同科研中心,上海,201318
- 作者简介：
- 基金信息：
- DOI：
  CLC： TP212;O657
- Published：2026
- 稿件说明：
移动端阅览
QUE Longbin, Gu Xin, PAN Hongzhi. Research progress of MOFs-based aptamer sensors in detection of tumor markers[J]. 2026, 45(2): 1-5.
DOI：

QUE Longbin, Gu Xin, PAN Hongzhi. Research progress of MOFs-based aptamer sensors in detection of tumor markers[J]. 2026, 45(2): 1-5. DOI：

摘要

金属有机框架(MOFs)材料具有比表面积大、孔隙可调、易于制备等诸多优点，现已广泛用于传感器的构建。适配体是合成亲和DNA和RNA的生物识别元件，具有非特异性结合位点少、结合力高、修饰简单的优势，广泛用于传感器的构建。近年，MOFs基适配体传感器在肿瘤标志物检测方法上已引起公司和学者的普遍关注。为此，本文综述了肿瘤标志物、适配体传感器，重点介绍了MOFs基适配体传感器在检测肿瘤标志物方面的研究进展，并对未来用MOFs材料构建适配体传感器检测肿瘤标志物进行了展望。

Abstract

Metal-organic frameworks(MOFs)materials are now widely used in the construction of sensors

as they have many advantages such as large specific surface area

tunable pore size

and easy preparation.Aptamers are synthetic DNA and RNA affinity biorecognition elements with the advantages of fewer non-specific binding sites

high binding strength and simple modification

which are widely used in the construction of sensors.In recent years

MOFs-based aptamer sensors have attracted widespread attention from companies and scholars for tumor marker detection methods.For this reason

this paper reviews tumor markers

aptamer sensors

and highlights the research progress of MOFs-based aptamer sensors in detection of tumor markers

and proepects the future construction of aptamer sensors for the detection of tumor markers with MOFs materials.

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