LIU Xian-hua, SHI Xiao-xuan, YANG Jiao-feng, et al. Design and realization of Ag nanoparticles-based LSPR sensor device[J]. 2014, 33(1): 72-74+81. DOI: 10.13873/j.1000-97872014.01.034.
基于Ag纳米粒子的LSPR传感器装置设计与实现
摘要
设计了一种集原位芯片制备和在线检测于一体的局域表面等离子体共振(LSPR)生物传感器装置
减少了检测过程中芯片移动产生的误差
并实现了小型化、在线化、简易化的目标。在该装置上利用电沉积法制备了Ag纳米粒子的LSPR芯片
实验测试结果表明:氧化铟锡(ITO)层厚度为23±5 nm时
在-1.4 V电位
制得折射率灵敏度为246 nm/RIU的LSPR芯片。
Abstract
A localized surface plasmon resonance(LSPR) biosensor devices which integrates in-situ chip preparation and online detection is designed
which reduces error caused by movement of chip in detection process and realizes device miniaturization
online detection
and simplification. Electrodeposition method is used to prepare Ag nanoparticle LSPR chips in this device
experimental results show that when the potential is -1. 4 V
the thickness of ITO layer is 23 ± 5 nm
the refractive index sensitivity of LSPR chips reaches 246 nm / RIU.