HOU Chang-jun, SONG Kun, PENG Jian, et al. Research on rapid detection of lung cancer markers based on colorimetric sensor array system[J]. 2012, 31(9): 57-59+63.
HOU Chang-jun, SONG Kun, PENG Jian, et al. Research on rapid detection of lung cancer markers based on colorimetric sensor array system[J]. 2012, 31(9): 57-59+63. DOI: 10.13873/j.1000-97872012.09.013.
The early rapid diagnosis of lung cancer is very important for the treatment of patients with lung cancer.Colorimetric array sensor is used for detecting four specific breath gas markers of patients with lung cancer.The digital data library generated is analyzed with statistical and chemometric methods
including hierarchical cluster analysis(HCA) and principal component analysis(PCA).Different substances
volume fraction samples can be correctly classified in cluster analysis
and the different substances with similar structure and the same substances with approximate volume fraction will be preferentially gathered in a cluster.Though the first two principal components obtained by PCA only represent 72.0 % of the amount of markers information
all the samples can be distinguished from each other.It is a simple and efficient detection and identification method for lung cancer markers.
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