重庆大学生物工程学院
纸质出版:2012
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[1]罗小刚,汪德暖,刘静静.肺癌呼吸气体检测系统的气室设计[J].传感器与微系统,2012,31(01):90-93+96.
LUO Xiao-gang, WANG De-nuan, LIU Jing-jing. Design of gas chamber of lung cancer respiratory gas detection system[J]. 2012, 31(1): 90-93+96.
[1]罗小刚,汪德暖,刘静静.肺癌呼吸气体检测系统的气室设计[J].传感器与微系统,2012,31(01):90-93+96. DOI: 10.13873/j.1000-97872012.01.033.
LUO Xiao-gang, WANG De-nuan, LIU Jing-jing. Design of gas chamber of lung cancer respiratory gas detection system[J]. 2012, 31(1): 90-93+96. DOI: 10.13873/j.1000-97872012.01.033.
基于卟啉传感器阵列(PSA)的肺癌呼吸气体检测系统是通过采集处理PSA芯片表面图谱信息来对人体呼吸气体进行定性检测
达到早期肺癌诊断的目的。检测过程中
PSA芯片能否与气体分子快速、均匀结合将直接影响气体检测系统的准确度。以系统中PSA芯片与肺癌呼吸气体反应的气室为研究对象
借助CFD专用软件FLUENT对气室进行流场仿真结构优化
在气室理论模型的基础上
进行了气室实物制作
结果表明:通过采用抛物线形气室内腔、安装导流板、减小分流孔通径、适当加大分流孔倾斜角度等优化方案后
气室内呼吸气体呈层流流动状态
流场更加均匀、密集
能达到检测系统中PSA芯片与呼吸气体分子快速、均匀结合的要求。
Lung cancer respiratory gas detection system based on Porphyrin sensor arrays(PSAs)is used to detect human respiratory gases qualitatively through the acquisition and processing the information of PSA images
to achieve the purpose of early lung cancer diagnosis.In the detection process
whether PSA chips can bind gas molecules rapidly and uniformly
directly affects the accuracy of detection system.The chamber in which PSA chips reacts with lung cancer respiratory gases as the research object
is produced physically on the basis of the gas theoretical model with FLUENT which is a kind of CFD special software
simulating the gas chamber flow filed and optimizing its structure.The results show that the gas chamber using the optimization options of parabolic chamber cavity
installation of guide plates
reducing the diameter of diversion holes and increasing the tilt angle of diversion holes appropriately
in which the respiratory gases show a laminar flow state and the flow field is more uniform and dense
can achieve the requirements of PSA chips binding with gas molecules rapidly and uniformly.
多点测量式毒气阵列检测系统研究与光谱分析 [J]. 廖海洋,吕建波,侯长军,张红英,朱彬. 光电工程 . 2009(01)
卟啉传感器检测挥发性有机化合物的研究进展 [J]. 侯长军,段玉娟,霍丹群,任桂香. 传感器与微系统 . 2008(07)
卟啉传感器研究进展 [J]. 侯长军,张红英,霍丹群,吉永超. 传感器与微系统 . 2008(03)
呼吸气体检测在肺癌早期诊断中的应用 [J]. 应可净,黄强. 国际呼吸杂志 . 2006(02)
Molecular interactions of monosulfonate tetraphenylporphyrin (TPPS 1 ) and meso-tetra(4-sulfonatophenyl)porphyrin (TPPS) with dimethyl methylphosphonate (DMMP) [J] . Danqun Huo,Limin Yang,Changjun Hou,Huanbao Fa,Xiaogang Luo,Yi Lu,Xiaolin Zheng,Jun Yang,Li Yang. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy . 2009 (2)
Towards the development of a portable device for the monitoring of gaseous toxic industrial chemicals based on a chemical sensor array [J] . Patrick Kim,Jeffrey D. Albarella,James R. Carey,Matthew J. Placek,Avijit Sen,Aaron E. Wittrig,William B. McNamara. Sensors & Actuators: B. Chemical . 2008 (1)
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