Aimed at the deficiency in the existing cell-elctrofusion devices

a microsystem technology-based high-efficiency and automatic cell-electrofusion device is developed.MEMS technique fabricated cell-electrofusion chip is integrated with signal generator

in which precisely designed microstructure and signal are used for locating cells.In this chip

small distance between one pair of microelectrodes reduces required voltage.Many different-size microelectrodes can be chosen in this device.Cell fusion can also be observed and manipulated under microscope.According to the result in the on-chip cell-fusion experiments

up to 40% fusion efficiency is obtained.