LIU Xiaowei, TIAN Li, HUO Mingxue, et al. Design of integrated capillary electrophoresis chip[J]. 2003, (2): 61-64. DOI: 10.13873/j.1000-97872003.02.022.
集成毛细管电泳芯片的设计
摘要
利用ANSYS软件对集成毛细管电泳芯片微沟道内样品流动情况进行模拟
获得了不同进样模式下微沟道的结构与流体流速之间的关系
并以此为依据对芯片整体结构参数进行设计:毛细管沟道最终尺寸为宽度16μm
深度10μm
有效分离长度为3.5cm的圆角转弯形沟道
从而确定整个芯片设计。
Abstract
?The fluid distribution in the microchannel of ICEC (Integrated Capillary Electrophoresis Chip) was simulated using ANSYS software.The relations between the microchannel structure and flow velocity under different sample injection modes were obtained.Then the optimized channel structure was chosen by the width of 16?μm
the depth of the chip was determined 10?μm and the effective dividing length of 3.5?cm with round corner channel.The chip structure was designed.