?A microdialysis glucose sensor system based on coimmobilizing technique has been developed
and factors crucial to the system’s response characteristics are evaluated in ex vivo experiments
namely
the immobilizing technique and the flow rate. The optimized system has adopted a graduated ("sandwich") immobilizing method to coimmobilize glucose oxidase with peroxidase on the silicon wafer of Au interdigital electrode
and the flow rate is chosen to be at 20?μl/min.The system offers good linearity
In vivo measurement of subcutaneous glucose concentrations with an enzymatic glucose sensor and a wick method [J] . J. Brückel,W. Kerner,H. Zier,G. Steinbach,E. F. Pfeiffer. Klinische Wochenschrift . 1989 (9)