1. 常州大学生物医学工程与健康科学研究院
2. 常州大学医学与健康工程学院
3. 常州市第三人民医院
纸质出版:2025
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刘磊, 李轩, 车波, 等. 基于家用呼吸机的高频振荡排痰系统研究[J]. 传感器与微系统, 2025,(8):101-104+109.
刘磊, 李轩, 车波, 等. 基于家用呼吸机的高频振荡排痰系统研究[J]. 传感器与微系统, 2025,(8):101-104+109. DOI: 10.13873/J.1000-9787(2025)08-0101-04.
针对呼吸道患者气道黏液清除困难,长期治疗费用高等问题,设计了一种基于家用呼吸机的高频振荡排痰系统。在呼吸机正压通气下,该系统通过控制扬声器振荡源的频率、幅值产生周期性振荡气流作用于人体气道,体外模拟小气道黏液栓实验表明:该系统可以通过流体剪切力移动和稀化黏液栓。同时在不影响排痰效果情况下,提出了低幅高频的保护性通气优化策略,规避了高气道压导致的肺部气压伤风险。该系统操作简单,价格便宜,尤其适合中重度慢性阻塞性肺疾病、囊性纤维化等黏液潴留慢性呼吸道疾病患者使用,具有重要的临床应用价值。
吕东锴,廖舒琅,王聪,刘科,刘格格.基于LabVIEW的高冲击加速度校准系统设计与实现[J].传感器与微系统,2024(10).
刘磊,潘洁,王予新,邓林红.基于电磁感应自驱动传感器的呼吸率监测系统研究[J].传感器与微系统,2024(06).
陈新茹,杨波.基于3D打印的隧道磁阻加速度计研究[J].传感器与微系统,2023(12).
吴静静.排痰仪联合气道管理对老年肺炎患者痰液黏稠度、肺功能及血气指标的影响[J].黑龙江中医药,2023(04).
王蕾,邱宇,王娟,杨谨羽,吴小玲.无创高频振荡通气在中-重度慢性阻塞性肺疾病急性加重期伴呼吸衰竭患者中的应用[J].成都医学院学报,2022(01).
袁越阳,周理,刘炜,戴征,陈宇清.高频震荡通气技术研究现状分析与展望[J].生物医学工程学杂志,2021(01).
Zheng Zeguang,Yang Kai,Liu Ni,Fu Xiuhua,He Huijie,Chen Hong,Xu Peijun,Wang Jing,Liu Maofeng,Tang Yuling,Zhao Fengzi,Xu Shufeng,Yu Xiaowei,Han Jichang,Yuan Bo,Jia Bin,Pang Guifen,Shi Yantong,Kuang Min,Shao Haiyan,Xiong Hao,He Jia,Pan Yuanyuan,Chen Rongchang.Evaluation of safety and efficacy of inhaled ambroxol in hospitalized adult patients with mucopurulent sputum and expectoration difficulty.[J].Frontiers in medicine,2023.
MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom,Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, Kings College London, London, United Kingdom.,Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, London, United Kingdom.,MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom,Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, Kings College London, London, United Kingdom.,MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom,Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, Kings College London, London, United Kingdom.,Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, London, United Kingdom.,Division of Health and Social Care Research, King's College London, London, United Kingdom,NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom.,Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, London, United Kingdom.,MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom,Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, Kings College London, London, United Kingdom,Institute for Lung Health, University of Leicester, Leicester, United Kingdom.,MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom,Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, Kings College London, London, United Kingdom,NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom. Electronic address: anne.greenough@kcl.ac.uk..An in vitro investigation of the inflammatory response to the strain amplitudes which occur during high frequency oscillation ventilation and conventional mechanical ventilation[J].Journal of Biomechanics,2019.
Nikhil Bansal,Abhinav Singh Chauhan,Ramesh Pariyarath Menon.A learning experience in the use of high-frequency oscillatory ventilation in infants post-cardiac surgery[J].Indian Journal of Thoracic and Cardiovascular Surgery,2019.
School of Automation Science and Electrical Engineering, Beihang University, Beijing, China.,School of Automation Science and Electrical Engineering, Beihang University, Beijing, China.,The State Key Laboratory of Fluid Power Transmission and Control, Zhejiang University, Hangzhou, China.,Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China.,School of Automation Science and Electrical Engineering, Beihang University, Beijing, China.,Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China.,Department of Statistical Science, Duke University, Durham, NC, USA.,Faculty of Health Sciences, University of Macau, Taipa, Macau..ANSYS-MATLAB co-simulation of mucus flow distribution and clearance effectiveness of a new simulated cough device.[J].International journal for numerical methods in biomedical engineering,2018.
Tatkov Stanislav,Pack Rodger J.Symmetrical-waveform high-frequency oscillation increases artificial mucus flow without changing basal mucus transport in in vitro ovine trachea.[J].Respiratory care,2011.
Iguchi Naoya,Hirao Osamu,Uchiyama Akinori,Mashimo Takashi,Nishimura Masaji,Fujino Yuji.Evaluation of performance of two high-frequency oscillatory ventilators using a model lung with a position sensor.[J].Journal of anesthesia,2010.
Volpe Marcia S,Adams Alexander B,Amato Marcelo B P,Marini John J.Ventilation patterns influence airway secretion movement.[J].Respiratory care,2008.
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