天津大学生命科学学院
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李文娜, 秦怡, 彭伟盼. MicroRNA检测方法研究进展[J]. 传感器与微系统, 2024,(3):1-5+13.
李文娜, 秦怡, 彭伟盼. MicroRNA检测方法研究进展[J]. 传感器与微系统, 2024,(3):1-5+13. DOI: 10.13873/J.1000-9787(2024)03-0001-05.
MicroRNA(miRNA)是一类广泛存在于真核细胞中的单链非编码小RNA
在机体中通过诱导mRNA降解或调节蛋白质水平调控基因表达。研究表明,miRNA的异常表达与多种人类疾病密切相关,可作为早期诊断和疾病筛查理想的生物标志物,因此,实现miRNA早期精准检测在临床诊断和医学研究中具有重要意义。本文围绕传统检测方法与新型miRNA生物传感器两方面,总结了miRNA检测方法的研究成果,并提出了未来的发展趋势。
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