1. 桂林电子科技大学机电工程学院
2. 中国科学院深圳先进技术研究院生物医学与健康工程研究所
3. 南方科技大学工学院
纸质出版:2024
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宋忠义, 蒋占四, 刘楚, 等. 磁性微球机器人在模拟血液中的运动控制[J]. 传感器与微系统, 2024,(1):17-20+24.
宋忠义, 蒋占四, 刘楚, 等. 磁性微球机器人在模拟血液中的运动控制[J]. 传感器与微系统, 2024,(1):17-20+24. DOI: 10.13873/J.1000-9787(2024)01-0017-04.
微纳机器人因其尺寸小、操控精度高、易到达小腔道等优点,可精确、高效地递送药物,是未来精准医学的新方向。本文以明胶为基材,构建了磁性微球机器人系统,它兼具明胶对环境无毒、无污染、生物可降解的优点,以及磁场对生物组织无害、不与物质直接接触而实现控制等优点。通过优化制备条件如明胶浓度、搅拌速度和乳化剂的浓度及乳化时间,制备出稳定、均匀的明胶磁性微球。研究了粒径、磁场强度、频率及液体粘度对粒子运动的影响,进一步探讨了粒子在不同浓度的模拟血液中的运动控制。今后,可以结合机器视觉、自动识别导航等从而真正体现微纳技术的优势,有望获得广阔的医学应用前景。
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