Aiming at the needs of a variety of bioelectricity acquisition such as electroencephalogram（ EEG）electrocardio signals and feedback in basic medicine

use highly integrated analog front-end scheme

a closed-loop feedback control method based on bioelectricity is proposed

and specific circuit implementation and system design is given. The experimental results show that the signal acquisition range of this system is between ± 2. 5 V

and the precision can reach 0. 5 μV

which is consistent with the results of standard instruments. The precision of bioelectric feedback is 0. 1 V in range of ± 5 V. Closed-loop control experiments show that the system can feedback adjustable electrical stimulation in real time. The system has a size of 14 cm × 6 cm × 2 cm and a weight of 292 g.Combined with 5 000 m Ah lithium battery

the system can work continuously for one week. Its wireless spacious control distance is 45 m

which meets the needs of multi-type bioelectricity acquisition

wireless adjustable electric pulse feedback and closed-loop real-time control.