1. 北京信息科技大学仪器科学与光电工程学院
2. 北京信息科技大学北京市重点实验室(机电系统测控)
纸质出版:2020
移动端阅览
[1]杨海涛,刘桂礼,孔全存,李东.基于微流控芯片荧光成像检测仪研制[J].传感器与微系统,2020,39(09):77-79+83.
Research and fabrication of fluorescence imaging detector based on micro-flow control chip[J]. 2020, 39(9): 77-79+83.
[1]杨海涛,刘桂礼,孔全存,李东.基于微流控芯片荧光成像检测仪研制[J].传感器与微系统,2020,39(09):77-79+83. DOI: 10.13873/J.1000-9787(2020)09-0077-03.
Research and fabrication of fluorescence imaging detector based on micro-flow control chip[J]. 2020, 39(9): 77-79+83. DOI: 10.13873/J.1000-9787(2020)09-0077-03.
针对激光诱导荧光检测系统结构体积大、成本高且不利于推广应用的缺点
提出以共聚焦光路结构成像原理为基础
将LED作为激发光源并结合Zemax光学设计优化光路结构尺寸。在降低系统成本的同时达到了使其结构更加紧凑、体积较小的设计效果。同时减小了激发光能量在结构中的损失
有效地提高了系统的信噪比
顺应了POCT医疗仪器小型化、低成本、便携式的发展趋势。
Aiming at the shortcoming that the structure of laser induced fluorescence detection system is large in volume
high in cost and not conducive to popularization and application
optimize the structure size of optical path based on the principle of confocal optical path structure imaging is proposed
using LED as excitation light source combined with Zemax optical design. While reducing the cost of the system
the design effect of making its structure more compact and smaller is achieved. At the same time
the loss of excitation light energy in the structure is reduced
the signal-to-noise ratio of the system is improved effectively
and the development trend of miniaturization
low cost and portable of point-of-care testing( POCT) medical instrument is complied with.
基于CCD传感器的香菇动态去根系统 [J]. 高汉斌,吕浩杰,韩现伟,张镭. 传感器与微系统 . 2018(09)
图像分析在液滴检测技术中的应用 [J]. 陈海秀,成顶,胡祯林. 传感器与微系统 . 2016(04)
基于微流体芯片用于单个DNA分子检测的共焦激光诱发荧光系统(英文) [J]. 彭志勇. 石河子大学学报(自然科学版) . 2014(03)
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基于光学共聚焦原理的便携式荧光检测装置 [J]. 刘剑,刘常春. 仪表技术与传感器 . 2010(08)
共聚焦激光诱导荧光检测系统的研究 [J]. 冯金垣,区伟能,付治新. 半导体光电 . 2008(06)
微流控芯片及有机发光二极管荧光检测系统的研究 [D]. 姚波. 清华大学 2006
微流控芯片高灵敏度激光诱导荧光检测系统的研究及其在集成生化分析系统中的应用 [D]. 富景林. 浙江大学 2006
Confocal laser-induced fluorescence detector for narrow capillary system with yoctomole limit of detection [J] . Mitchell T. Weaver,Kyle B. Lynch,Zaifang Zhu,Huang Chen,Joann J. Lu,Qiaosheng Pu,Shaorong Liu. Talanta . 2017
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