To solve the problem of instable compression rate of different samples which caused by the fixed encoding precision

an electrocardio（ ECG） signal compression application specific IC（ ASIC） circuit with selfadjustable encoding precision based on 5/3 lifting wavelet is proposed. It can self-adjust coding precision dynamically according to the dithering degree of ECG signal

and stabilize the compression rate at a higher level. A reverse scanning mechanism is proposed to avoid the recursive operation of embedded zerotree wavelet（ EZW）encoding and it further reduces the complexity of the circuit. The proposed design only has degree of distortion of3. 86 %

while compression rate is 23. 91. In 40 nm CMOS process

the ASIC implement only has 9 885 equivalent gate count

with a power consumption of 7. 11 μW at 1. 1 V voltage.