MEMS accelerometer and gyro are important measurement components of inertial navigation system（ INS）. In order to improve measurement precision of INS

it is necessary to calibrate its various parameters before using accelerometer. On the basis of construction of an ideal model between output of three-axis MEMS acceleration sensor

gravity acceleration values

zerobias and scale factor

according to relationship between modulus value of the acceleration of gravity in each axis component and gravity when accelerometer is in stationary state

propose a six-posture calibration method of zero-bias and scale factor

and establish calibration equation. The method is proved to be correct through experimental verification taking MPU6050 acceleration gyroscope as example. The results show that the callbration method can effectively improve precision of technical indicators of acceleration sensor such as zero-bias and scale factor by the calibration method.